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💼 Hands that work as hard as you do—hydrated, protected, unstoppable.
Prequel Skin Hand Cream is a dermatologist-developed, clinically tested moisturizer designed for dry, cracked hands. Featuring lipid layer enhancers and a proprietary water-resistant formula, it delivers 24-hour hydration and creates a flexible barrier to prevent moisture loss—even after frequent handwashing. Lightweight, fragrance-free, and suitable for all skin types, this fast-absorbing balm is ideal for professionals who demand effective, non-greasy hand care on the go.













| ASIN | B0CYDGC42H |
| Active Ingredients | Lipid Layer Enhancers |
| Age Range (Description) | Adult |
| Age Range Description | Adult |
| Best Sellers Rank | #13,594 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #46 in Hand Creams & Lotions |
| Brand | Prequel |
| Brand Name | Prequel |
| Country as Labeled | United States |
| Customer Reviews | 4.4 out of 5 stars 833 Reviews |
| Item Dimensions | 1.25 x 2.25 x 6.75 inches |
| Item Form | Lotion |
| Item Highlight | Hand Cream For Dry Cracked Hands With Moisture Lock Formula, Unscented Non Greasy Balm For Hydrating Skin Barrier Support |
| Item Volume | 3.4 fluid ounces |
| Item dimensions L x W x H | 1.25 x 2.25 x 6.75 inches |
| Manufacturer | Prequel Skin |
| Material Features | Allergy Tested |
| Material Type Free | Fragrance Free |
| Number of Items | 1 |
| Other Special Features of the Product | Lightweight |
| Product Benefits | Creates flexible film to prevent water loss and dryness. |
| Recommended Uses For Product | Help prevent moisture loss by using after hand washing. |
| Scent Name | Fragrance Free |
| Skin Type | All, Dry, Normal, Oily, Sensitive |
| Special Feature | Lightweight |
| Special Ingredients | Lipid Layer Enhancers |
| Specific Uses For Product | Dryness |
| Target Use Body Part | Hands |
| UPC | 810129110203 |
| Unit Count | 3.4 Fluid Ounces |
C**K
Nice hand cream, stays on.
I use this hand cream on top of another hand cream to lock in the hydration when my hands are extra dry from the winter months. The hydration is still there after several hand washes. Great for nighttime hydration as well. Non-greasy. Does not sting irritated or chapped hands. Hands look moisturized and smooth.
M**A
10/10! So great!
This works great for my daughters dry cracked hands! When i put it on it instantly makes then moisturized and soaks in fast so its not greasy or annoying, and does not irritate her skin! Its a nice consistency too! Also no strong scent, so great for people who are sensitive to fragrance! Great product would recommend!! How I rate the products- 5 Stars = Exceeded my expectations. Love it and will buy again. 4 Stars = Exactly what I was looking and hoped for. Some issues. 3 Stars = Satisfactory. Minor, acceptable issues but it does the job. 2 Stars = Wouldn't recommend or buy again. May work for you but did not for me. 1 Stars = Complete waste of a product. Went to trash
K**L
Perfect for dry cracked hands
The ONLY thing that works on my ridiculously dry cracked hands. dries fast works great even thru all my hand washing.
M**E
Good hand cream
This hand cream is different than any I’ve used before. It comes in a larger tube than I expected, and I felt like it was a great value for the money. It’s very lightweight, and it doesn’t leave your hands feeling greasy or slimy. I love the way it dries down. For this reason, though, it doesn’t feel quite as moisturizing as some other creams. It does protect your hands when you wash them later, so that’s a trade off. I will definitely repurchase.
G**E
Moisturizing Cream
Love this cream. Moisturizes hands and cracked feet. Slight fragrance, lightweight cream and smooth consistency. Great value for the money.
S**R
The only hand cream worth buying
This is the best hand cream we have ever used. It is light but hydrating and long lasting. My hubby has eczema on his hands which is aggravated from washing. Using this regularly has healed his skin. Such great value for money. Smells good too. (I have used this on my face, but ask your dermo before copying me)
L**C
It's fine but wouldn't repurchase
It’s an okay hand cream. It provides some moisture and has a smooth, lightweight texture, but I don’t find it to be as water-resistant as it claims. I do appreciate that it’s unscented and comes in a generous size, but it’s just not nourishing enough for my dry hands.
O**E
Keeps My Hands Feeling Soft and Protected
This hand cream has earned a permanent spot on my desk, and I use it multiple times throughout the day. My hands tend to get irritated easily, especially during the colder months, so I'm always looking for something that provides lasting moisture without feeling heavy. What I like most is that it seems to create a protective layer on my skin that doesn't immediately disappear after washing my hands. My hands continue to feel comfortable and moisturized even after getting them wet, which isn't something I've experienced with many other hand creams. The formula is thick enough to feel nourishing, but it doesn't leave behind a greasy or sticky residue. I can apply it and get right back to typing, using my phone, or handling paperwork without feeling like I need to wipe my hands off first. I also appreciate that it's unscented, absorbs well, and leaves my skin feeling soft and smooth. A little goes a long way, so the tube lasts quite a while even with daily use. If you're looking for a hand cream that provides lasting moisture without the greasy feel, this one is definitely worth trying.
B**N
Did not suit me
It didn’t moisturise my hands. In fact , my hands felt drier than when I used cheaper ones. I definitely WONT be buying again.
L**L
Reasonable but not remarkable
Good moisturizer but nothing better than cheaper ones I've bought locally. I'd give it 7/10 in all areas
A**R
No!
Not recommended. Leaves my hands feeling dry and flakes as well.
Trustpilot
2 weeks ago
1 month ago